Notes of Prulifloxacin (Pruquin)
Each year an estimated 10 million travelers, mainly to developing countries, develop traveler's diarrhea. The illness can be caused by a known pathogen, or the pathogen might never be identified. In 5% to 10% of cases, the illness progresses to irritable bowel syndrome that can last from weeks, to months, to years, and even to decades, according to Dr. DuPont. "More than half of these people are still sick as many as 6 years later."
Several antibiotic treatments are available for the treatment of traveler's diarrhea. But shortcomings of available therapies, such as inadequate bacterial coverage, increasing bacterial resistance, and problems with patient compliance, highlight a need for alternatives. The drug's once-daily, 3-day regimen is patient-friendly.
